CYP2E1Polymorphism and Better Outcome after Methanol Poisoning

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Methanol poisoning.

A 22-year-old male presented with acute onset vomiting, diarrhea, abdominal pain and altered sensorium. He had a history of acute alcohol intake (locally made with solvent) a day prior to the presentation. Biochemical investigations revealed severe metabolic acidosis. Diagnosis of methanol poisoning was made on the basis of history and biochemical abnormality. Magnetic resonance imaging (MRI) d...

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Risk factors related to poor outcome after methanol poisoning and the relation between outcome and antidotes--a multicenter study.

INTRODUCTION. Thorough prognostic and metabolic studies of methanol poisonings are scarce. Our aims were to evaluate the factors associated with sequelae and death from methanol poisoning, to develop a simple risk-assessment chart to evaluate factors associated with sequelae and death from methanol poisoning, and to compare the antidotes ethanol and fomepizole. PATIENTS AND METHODS. We present ...

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Methanol poisoning.

Methanol poisoning is an uncommon but an extremely hazardous intoxication. Since methanol is a versatile fuel and is having increasing usage in an energy-conscious society, a high index of suspicion and swift laboratory confirmation is essential in managing this poisoning. Methanol poisoning may occur in sporadic or epidemic circumstances. Chronic exposure may occur in the occupational setting....

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Methanol poisoning and long term sequelae – a six years follow-up after a large methanol outbreak

BACKGROUND Mass poisonings with methanol are rare but occur regularly both in developed and in developing countries. Data from the poisoning episodes are often published, but follow-up-data is scarce. We therefore conducted a six year follow-up study after the large methanol outbreak in Estonia in September 2001. METHODS Surviving victims from the outbreak were contacted and invited to an int...

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Visual evoked potentials in patients after methanol poisoning.

OBJECTIVES We report the results of the visual evoked potentials (VEP) examination in patients after severe poisoning by methanol. MATERIAL AND METHODS The group of 47 patients (38 males and 9 females) was assembled out of persons who survived an outbreak of poisoning by the methanol adulterated alcohol beverages, which happened in the Czech Republic in 2012-2013. The visual evoked potentials...

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ژورنال

عنوان ژورنال: Basic & Clinical Pharmacology & Toxicology

سال: 2015

ISSN: 1742-7835

DOI: 10.1111/bcpt.12408